Tropokine™
Tropokine™ is a next-generation autologous conditioned serum therapy, developed using the proven Tropocells® PRF platform. It is designed to control inflammation and support natural tissue regeneration—safely, effectively, and with biological precision.
Using a simple, single-spin preparation, Tropokine™ concentrates IL-1Ra (Interleukin-1 Receptor Antagonist)—a powerful, naturally occurring cytokine that blocks IL-1 signaling and promotes healing.
How It Works
Elevated levels of Interleukin-1 (IL-1) in damaged tissue bind to IL-1 receptors, triggering a cascade of inflammation, pain, and cartilage degradation.
Tropokine™ delivers a concentrated dose of IL-1Ra, which binds to IL-1 receptors and blocks inflammatory signalling.
IL-1Ra competitively blocks IL-1 receptors, restoring the inflammatory balance. Other autologous growth factors may also help protect cartilage and slow joint degeneration.
Why Tropokine™?
No additives or foreign substances
Trusted platform with consistent results
Hyper-concentrated anti- inflammatory cytokine
Efficient and easy-to-use process
Safe and well-tolerated injection-based therapy
Biologically compatible with the patient’s body
Evidence-based Indications
Tropokine™ is suitable for a wide range of musculoskeletal and inflammatory conditions, supported by clinical and preclinical evidence.
- Osteoarthritis (knee, hip, shoulder, ankle, etc.)
- Tendinopathies (Achilles, patellar, rotator cuff)
- Post-traumatic cartilage lesions
- Discogenic pain and spinal osteoarthritis
- Post-surgical inflammation (e.g., after arthroscopy or ACL repair)
- Chronic synovitis and joint effusions
- Muscle injuries and tendinitis
Tropokine™ Preparation





